Acanthosis nigricans is a disorder that may begin at any age and usually being of overweight. Some cases are genetically inherited. It is most common among people of African descent.Acanthosis nigricans may begin at any age. Acanthosis nigricans can affect otherwise healthy people, or it can be associated with medical problems.

Causes of Acanthosis Nigricans

Acanthosis nigricans may begin at any age.
We do not know the exact cause of this condition.
Rarely the condition is associated with an endocrine disorder or a tumor.
Acanthosis nigricans is sometimes associated with being overweight.

Symptoms of Acanthosis Nigricans

Acanthosis nigricans usually appears slowly and doesn't cause any symptoms other than skin changes.

Eventually, dark, velvety skin with very visible markings and creases appears in the armpits, groin, and neck. Sometimes, the lips, palms, soles of feet, or other areas may be affected.

Diagnosis of Acanthosis Nigricans

Your physician may recommend blood tests, endoscopy, X-ray or other tests studies to eliminate the possibility of underlying diabetes or cancer.

Treatment of Acanthosis Nigricans

There are no specific treatment for acanthosis nigricans. Treating any underlying conditions may cause the skin changes to fade, however. If you are overweight, losing excess pounds can help. Sometimes dietary changes are helpful, too.

If you are concerned about the appearance of your skin, your doctor may prescribe a cream or lotion to help lighten the affected areas. Some of these lotions contain modified vitamin A products such as tretinoin (Retin-A) or other medications. Sometimes oral medications such as etretinate or isotretinoin (Accutane, others) are helpful. Fish oil supplements may also be recommended. Dermabrasion or laser therapy may help reduce the thickness of certain affected areas.

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